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WEEK 5
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WHYNFL GAME CENTER

San Francisco 49ers at Arizona Cardinals

Scheduled · Kickoff to be confirmed

2026 Regular season · Week 18 · State Farm Stadium

Latest game updateUpdated
San Francisco 49ers—Away
Arizona Cardinals—Home

Game details

Location
Glendale

Matchup preview

San Francisco 49ers 4–0 · Road 1–0 · Streak W4 · Power Index No. 1
Arizona Cardinals 1–3 · Home 0–1 · Streak L3 · Power Index No. 27
2026 regular season, per game · SF 4 games, ARI 4 games
MetricSFARI
Points per game30.52nd21.817th
Points allowed per game16.03rd29.329th
Total yards per game389.07th294.822nd
Passing yards per game251.813th204.522nd
Rushing yards per game137.36th100.521st
Turnovers per game0.53rd1.011th
Sacks allowed per game0.01st1.810th
Penalty yards per game43.34th75.028th

Highlighted values are the better side of each line; small figures are the league rank among clubs with games (1st = best). Points come from final scores; yardage, turnovers, sacks and penalties from team statistics.

San Francisco 49ers: recent results

  1. W 24–14 vs DEN Week 4
  2. W 36–30 vs ARI Week 3
  3. W 35–13 vs MIA Week 2
  4. W 27–7 @ LAR Week 1

Arizona Cardinals: recent results

  1. L 24–36 @ NYG Week 4
  2. L 30–36 @ SF Week 3
  3. L 7–31 vs SEA Week 2
  4. W 26–14 @ LAC Week 1

San Francisco 49ers: season leaders

Passing
Brock Purdy 1,007 yds
Rushing
Christian McCaffrey 218 yds
Receiving
George Kittle 244 yds
Sacks
Keion White 2.0

Arizona Cardinals: season leaders

Passing
Jacoby Brissett 818 yds
Rushing
Jeremiyah Love 223 yds
Receiving
Michael Wilson 258 yds
Sacks
Budda Baker 1.5

San Francisco 49ers: injury report

  • Out Brandon Aiyuk WR
  • Out Isaac Guerendo
  • Out James Thompson Jr. RDT
  • Out Kyle Juszczyk FB
  • Out Marques Sigle SS
  • Out Nick Bosa RDE
  • Questionable Upton Stout NB

16 on reserve lists. Latest entry Oct 9. Full report

Arizona Cardinals: injury report

  • Out Andrew Wingard FS
  • Out Marvin Harrison Jr. WR
  • Out Tip Reiman TE
  • Questionable Josh Minkins
  • Questionable Karson Sharar WLB
  • Questionable Walter Nolen III RDT
  • Questionable Xavier Weaver

12 on reserve lists. Latest entry Oct 9. Full report

Head-to-head since 1999

SF 29 · ARI 22 in 51 meetings (regular season and playoffs).

  1. 2026 · Week 3 ARI 30, SF 36
  2. 2025 · Week 11 SF 41, ARI 22
  3. 2025 · Week 3 ARI 15, SF 16
  4. 2024 · Week 18 SF 24, ARI 47
  5. 2024 · Week 5 ARI 24, SF 23

Full series history

From WHYNFL's results archive, which begins in 1999.

Game notes

Win probability

SF 82.6% · ARI 17.3%

Matchup quality 53.9 / 100

Model estimate, updated Sep 28, 2026. Not a WHYNFL prediction.

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