Lamar Jackson is ruled out with a right thumb injury after one play against the Bills, and Jake Ferguson hurts his ankle

Lamar Jackson’s return lasted one play. The Baltimore Ravens quarterback hurt his right thumb, on his throwing hand, on the first snap of Sunday’s game against the Buffalo Bills, went straight to the locker room and was ruled out about 15 minutes later. Tyler Huntley took over at quarterback in Orchard Park.

• Jackson was back after missing three games with an ankle injury, and he had practiced fully all week
• He was hit by Bills edge rusher Greg Rousseau and linebacker Terrel Bernard as he threw to Zay Flowers, and the pass came up short
• The Ravens first listed him as questionable to return with a right thumb injury, then ruled him out
• Elsewhere in the early games, Cowboys tight end Jake Ferguson (ankle), Jaguars safety Eric Murray (elbow) and Raiders cornerback Darien Porter (groin) were questionable to return, and Falcons receiver Drake London was cleared after a concussion check

What happened to Lamar Jackson

Jackson threw on Baltimore’s first offensive play and was sandwiched by Rousseau and Bernard as the ball came out. He walked to the sideline, dropped to a knee almost immediately and then headed to the locker room. Reporters at the game saw his right thumb bleeding and wrapped before he left the field. The Ravens called him questionable to return at 1:20 p.m. ET and ruled him out at 1:33 p.m. ET, which was 8:33 p.m. in Cairo.

It was Jackson’s first game since he hurt his ankle. He was a full participant in practice on Wednesday, Thursday and Friday, and head coach Jesse Minter said on Friday, “We do think we’ll have Lamar this week.” The team has not said how serious the thumb injury is or whether he will have tests after the game.

Jake Ferguson hurt as Dallas runs short at tight end

Ferguson walked to the locker room in the first quarter against the Arizona Cardinals with an ankle injury, and the Cowboys listed him as questionable to return. Dallas had already made Luke Schoonmaker (groin) inactive, so Brevyn Spann-Ford and James Mitchell are the only other tight ends available.

Other early-game injuries

• Jaguars safety Eric Murray (elbow) was questionable to return against the Colts
• Raiders cornerback Darien Porter (groin) was questionable to return against the Jets
• Falcons receiver Drake London was checked for a concussion against the Buccaneers, was cleared and went back in for Atlanta’s second drive

In-game injuries at a glance

What comes next

Baltimore will give an update on Jackson after the game, and Minter’s Monday press conference is the first chance for more detail. The late-window inactive lists come out about 90 minutes before the 4:05 and 4:25 p.m. ET kickoffs. The early Week 8 inactives are here.