Matt LaFleur said early signs point to an Achilles tear for the 33-year-old defensive tackle, a week after Green Bay lost Edgerrin Cooper to the same injury.
Chicago's coach would not commit to Williams starting in Atlanta after Tyson Bagent and Case Keenum combined for three interceptions as Green Bay won 31-7.
The Bears receiver had said Chicago wanted to make Green Bay quit. The Packers linebacker answered after a five-takeaway win at Lambeau Field.
Christian Watson caught two long touchdown passes, Xavier McKinney intercepted two passes and Chicago went through two quarterbacks at Lambeau Field.
Cincinnati declared Swayze Bozeman out, Chicago is unlikely to get Dayo Odeyingbo back, and the Giants are checking Colton Hood for a concussion, while Houston lost David Montgomery earlier in Nashville.
Two days after Ditka's death at 86, Chicago honors its Hall of Fame tight end and Super Bowl XX coach in the 214th meeting of the NFL's oldest rivalry.
Chicago's quarterback sits at Green Bay with an eye on next week, Washington gets its top receiver back but loses Stefon Diggs and three safeties, and Tennessee's rookie plays through a sore back.
The ankle injury Brooks suffered in Tampa Bay will keep him out at least four games and thins Green Bay's backfield again.
The former Saints first-round pass rusher asked Chicago to release him from its practice squad after playing 12 snaps against the Jets, ending a nine-season career with 25 sacks.
Caleb Williams is questionable after returning to limited practice Friday. Tyson Bagent remains the announced starter for Sunday’s game at Green Bay.
