Dan Campbell says White's injury does not look good, and receiver Tom Kennedy is also expected to miss time with a knee injury as Detroit heads into its bye.
Baltimore clears its top receiver and Marlon Humphrey for Sunday night against the Falcons, but six players, Lamar Jackson among them, are inactive. Atlanta dresses Jake Matthews, Divine Deablo and Samson Ebukam.
San Francisco won a seven-turnover game in Seattle when Cooper Kupp was ruled a yard short on the Seahawks' last chance, and Gracen Halton scored on a fumble in the end zone.
Detroit answered an early deficit with 24 second-quarter points, Jared Goff threw three touchdown passes, and the Lions head into their bye at 3-2 while Arizona falls to 1-4.
Denver scored the last 13 points at SoFi Stadium, turning a Herbert fumble and an interception into fourth-quarter field goals, and the Chargers fell to 0-5 under Jim Harbaugh.
Chicago's coach would not commit to Williams starting in Atlanta after Tyson Bagent and Case Keenum combined for three interceptions as Green Bay won 31-7.
