Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
The Indianapolis Colts beat the Arizona Cardinals 31–27 at home at Lucas Oil Stadium in Week 6 of the 2025 regular season on October 12, 2025. It was a one-score game at the finish, decided by 4 points.
The 58 combined points were the most in any game of Week 6.
The result moved the Colts to 5–1 and dropped the Cardinals to 2–4. It was the Cardinals’ fourth straight loss. The Cardinals finished 2025 at 3–14 and missed the playoffs. The Colts finished 2025 at 8–9 and missed the playoffs.
In their previous meeting, the Indianapolis Colts won 22–16 on December 25, 2021.
Written by WHYNFL from the final scores in its results archive, which begins with the 1999 season. Records, streaks and season results count regular-season and playoff finals.
Series Colts lead the series 4–2 after meeting No. 6 since 2005 Full series history
Pittsburgh will check Dowdle's toe in warmups, but Jaylen Warren is set to carry the load again, while Indianapolis expects its veteran receiver back from a groin injury.
Arizona will keep its 2024 first-round receiver out of Sunday's game against Detroit while the deal is completed, and the remaining dispute is reportedly over the year of a second-round pick.