Minnesota moved to 5-0 after Jones' fourth-quarter touchdown broke a 13-13 tie that New Orleans had forced with an 87-yard fumble return.
Minnesota's leading tight end was ruled out on the second snap at the Superdome, and its lead running back is questionable to return with a knee injury.
Jefferson returns from the ankle sprain that cost him the win over Miami, while Minnesota holds Addison and Odell Beckham Jr. out against the Saints.
New Orleans will add its greatest quarterback to the Superdome's Ring of Honor on Sunday, two months after his first-ballot enshrinement in Canton. He also receives his Hall of Fame ring during the ceremony.
New Orleans also called up receiver Cedric Tillman and tackle Easton Kilty from the practice squad for Sunday's home game against Minnesota.
Line judge Jeff Seeman will sit two games and referee Adrian Hill one after on-camera confrontations with players during Week 4.
The former Saints first-round pass rusher asked Chicago to release him from its practice squad after playing 12 snaps against the Jets, ending a nine-season career with 25 sacks.
Minnesota left guard Donovan Jackson tore the meniscus in his left knee against Miami and is expected to miss the rest of the regular season after surgery.
Carson Wentz started Minnesota’s September 20 win at Chicago. Kyler Murray returned in Week 3, and a later trade changed J.J. McCarthy’s status.
