Final · Kickoff
2022 Regular season · Week 11 · Azteca Stadium · International
Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
Explore the 2022 regular season
The San Francisco 49ers beat the Arizona Cardinals 38–10 at Azteca Stadium, a neutral site, in Week 11 of the 2022 regular season on November 21, 2022.
The result moved the 49ers to 6–4 and dropped the Cardinals to 4–7. It was the 49ers’ third straight win. The 49ers finished 2022 at 13–4 and lost in the NFC Championship Game. The Cardinals finished 2022 at 4–13 and missed the playoffs.
In their previous meeting, the Arizona Cardinals won 31–17 on November 7, 2021. When they met again, the San Francisco 49ers won 38–13 on January 8, 2023.
Written by WHYNFL from the final scores in its results archive, which begins with the 1999 season. Records, streaks and season results count regular-season and playoff finals.
Series 49ers lead the series 23–20 after meeting No. 43 since 1999 Full series history
Arizona will keep its 2024 first-round receiver out of Sunday's game against Detroit while the deal is completed, and the remaining dispute is reportedly over the year of a second-round pick.
San Francisco needed the spot to bring back Ogbo Okoronkwo, ending the four-time Pro Bowl pass rusher's stay after less than two weeks.
Line judge Jeff Seeman will sit two games and referee Adrian Hill one after on-camera confrontations with players during Week 4.
