Final · Kickoff
2025 Regular season · Week 11 · State Farm Stadium
Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
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The San Francisco 49ers beat the Arizona Cardinals 41–22 on the road at State Farm Stadium in Week 11 of the 2025 regular season on November 16, 2025.
The result moved the 49ers to 7–4 and dropped the Cardinals to 3–7. The 49ers finished 2025 at 12–5 and lost in the Divisional round. The Cardinals finished 2025 at 3–14 and missed the playoffs.
In their previous meeting, the San Francisco 49ers won 16–15 on September 21, 2025. When they met again, the San Francisco 49ers won 36–30 on September 27, 2026. The 49ers swept the 2025 season series.
Written by WHYNFL from the final scores in its results archive, which begins with the 1999 season. Records, streaks and season results count regular-season and playoff finals.
Series 49ers lead the series 28–22 after meeting No. 50 since 1999 Full series history
Arizona will keep its 2024 first-round receiver out of Sunday's game against Detroit while the deal is completed, and the remaining dispute is reportedly over the year of a second-round pick.
San Francisco needed the spot to bring back Ogbo Okoronkwo, ending the four-time Pro Bowl pass rusher's stay after less than two weeks.
Line judge Jeff Seeman will sit two games and referee Adrian Hill one after on-camera confrontations with players during Week 4.
