THE WHY BEHIND THE GAME
Buffalo Bills vs San Francisco 49ers.
Every meeting since 1999, regular season and playoffs.
The Bills and 49ers have met 7 times since 2001. Rarely close: only 1 of the 7 games were decided by 8 points or fewer. The Bills have won the last 3 meetings. The most recent meeting, in 2024, went to the Bills, 35–10.
- Regular season
- BUF 4 · SF 3
- Playoffs
- No meetings
- Home record
- BUF 2–1 · SF 2–2
- Points per meeting
- BUF 23.0 · SF 21.0
- Current streak
- BUF won the last 3
- BUF biggest win
- By 34 · BUF 41, SF 7 (2004)
- SF biggest win
- By 42 · BUF 3, SF 45 (2012)
Every meeting
| Season | Game | Score | Winner |
|---|---|---|---|
| 2024 | Week 13 | SF 10, BUF 35 | BUF |
| 2020 | Week 13 | BUF 34, SF 24 | BUF |
| 2016 | Week 6 | SF 16, BUF 45 | BUF |
| 2012 | Week 5 | BUF 3, SF 45 | SF |
| 2008 | Week 13 | SF 10, BUF 3 | SF |
| 2004 | Week 16 | BUF 41, SF 7 | BUF |
| 2001 | Week 12 | BUF 0, SF 35 | SF |
Results through (Eastern time).
From WHYNFL's results archive, which begins in 1999. Regular season and playoffs, counted by franchise: Raiders games include Oakland, Chargers games San Diego, Rams games St. Louis.