Washington (1-3-1) visits 5-0 San Francisco at 8:15 pm ET Monday on ABC. The 49ers will be without Dre Greenlaw and Deebo Samuel, and Nick Bosa could return.
San Francisco's +61 tops the board; Miami's -62 is the worst. Jacksonville, Minnesota and Kansas City join the margin leaders as MIA, TEN and LAC hunt win No. 1.
Five of the six major national power rankings we tracked put San Francisco on top after its win in Seattle. Below the 5-0 49ers, Minnesota lands anywhere from third to eighth and New England from fourth to 13th.
