Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
The Houston Texans beat the San Francisco 49ers 26–15 at home at NRG Stadium in Week 8 of the 2025 regular season on October 26, 2025.
The result moved the Texans to 3–4 and dropped the 49ers to 5–3. The 49ers finished 2025 at 12–5 and lost in the Divisional round. The Texans finished 2025 at 12–5 and lost in the Divisional round.
In their previous meeting, the San Francisco 49ers won 23–7 on January 2, 2022.
Written by WHYNFL from the final scores in its results archive, which begins with the 1999 season. Records, streaks and season results count regular-season and playoff finals.
Series 49ers lead the series 4–2 after meeting No. 6 since 2005 Full series history
Ravens linebacker Trenton Simpson, Jets safety Minkah Fitzpatrick and Broncos guard Ben Powers drew the largest fines, and five players were docked for hip-drop tackles.
The fullback has a hyperextended knee and a bone bruise from Sunday's win over Denver, and Kyle Shanahan will spread his role among the tight ends for the trip to Seattle.