Final · Kickoff
2021 Regular season · Week 16 · Nissan Stadium · Thursday Night
Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
Explore the 2021 regular season
Series Series tied 3–3 after meeting No. 6 since 1999 Full series history
San Francisco won a seven-turnover game in Seattle when Cooper Kupp was ruled a yard short on the Seahawks' last chance, and Gracen Halton scored on a fumble in the end zone.
DeMeco Ryans said his lead back may miss time, leaving Woody Marks to carry the load as Houston heads to Jacksonville with Marvin Harrison Jr. on the way.
The 49ers linebacker was sent off midway through the second quarter after a sideline scrum, and San Francisco still took a 21-13 lead into halftime.
