Historical final score from the WHYNFL results archive. WHYNFL preserves the team labels of the time and converts supplied Eastern kickoff times. Team links open today's franchise hubs. Historical box scores and play-by-play are not supplied.
The Houston Texans beat the San Francisco 49ers 26–15 at home at NRG Stadium in Week 8 of the 2025 regular season on October 26, 2025.
The result moved the Texans to 3–4 and dropped the 49ers to 5–3. The 49ers finished 2025 at 12–5 and lost in the Divisional round. The Texans finished 2025 at 12–5 and lost in the Divisional round.
In their previous meeting, the San Francisco 49ers won 23–7 on January 2, 2022.
Written by WHYNFL from the final scores in its results archive, which begins with the 1999 season. Records, streaks and season results count regular-season and playoff finals.
Series 49ers lead the series 4–2 after meeting No. 6 since 2005 Full series history
Chicago's quarterback sits at Green Bay with an eye on next week, Washington gets its top receiver back but loses Stefon Diggs and three safeties, and Tennessee's rookie plays through a sore back.
Arizona will keep its 2024 first-round receiver out of Sunday's game against Detroit while the deal is completed, and the remaining dispute is reportedly over the year of a second-round pick.
Ravens linebacker Trenton Simpson, Jets safety Minkah Fitzpatrick and Broncos guard Ben Powers drew the largest fines, and five players were docked for hip-drop tackles.